Most children with MIS-C experienced only mild coronavirus symptoms prior to inflammatory illness: study
April 07, 2021 at 16:18
Most children who developed the rare but serious multisystem inflammatory syndrome in children (MIS-C) that occurs weeks following a coronavirus infection had no or only mild symptoms of COVID-19 when they were initially infected, according to a new study that’s said to be the largest analysis of such cases in children in the U.S.
The study included children up to age 20, though most were younger than 15.
The vast majority of children with MIS-C recover, though some may require hospitalization.
The study authors found that the majority of the patients studied — about 75% — did not experience symptoms of COVID-19 when they had a coronavirus infection.
However, when the patients later developed MIS-C, typically some two to five weeks later, fever was among the most common symptoms, the CDC analysis found.
These symptoms were least common among children up to age 4, who were also less likely to require intensive care than older children.
The CDC in the study said their findings add to existing theories that MIS-C is likely a delayed immune response to a COVID-19 infection.
The geographic and temporal association of MIS-C with the COVID-19 pandemic suggested that MIS-C resulted from delayed immunologic responses to SARS-CoV-2 infection.
The clinical manifestations varied by age and by presence or absence of preceding COVID-19," per the study.
CLICK HERE FOR COMPLETE CORONAVIRUS COVERAGETreatments for MIS-C often include steroids to reduce inflammation.
Experts have stressed that coronavirus vaccines are the best way to prevent COVID-19 infections, with COVID-19 vaccine studies in children currently underway.
"The clinical manifestations of patients with MIS-C varied by age and presence or absence of preceding COVID-19.